POS-626 IMPROVING CATHETER SURVIVAL IN CRBSI WITH ALCOHOL CATHETER LOCK SOLUTION

Despite the advocation of fistula first strategy, over 80 % incident dialysis patients initiate with tunnelled catheters (TDC) and 30 remain catheter dependent. related blood stream infection (CRBSI) is a dreaded complication reported incidence rate 1.1 to 5.5 per 1000 days. Conventionally management CRBSI includes IV antibiotics along antibiotic lock solution. this 30-50 require removal, especially in setting staphylococcal, pseudomonas, fungal infection. Literature does mention benefit alcohol locks solution but there no published data on its use. This study aimed compare efficacy safety 70% (ACL) vs management. All TDC as vascular access were followed for CRBSI. was diagnosed if appropriate clinical patient had two cultures (from venous hub circuit or peripheral vein) positive same organism other obvious focus infection.During received either instilled after each session which 3 consecutive If became asymptomatic days, kept remained symptomatic even days therapy hemodynamic compromise, removed. 225 duration 24010 34 developed Twenty (Group A) 12 B) ACL instead lock. Demographic profile group A & B given table 1. Group 11 males females mean age 61.36 ± 8.54 years. 5 7 58 16.94 Of 22 A,15 required removal B, none (P= 0.0095 ). After follow up 84.16 44.62 relapse any dysfunction. Based our pilot study, we found be far superior than effect performance life short term follow-up. We recommend during episodes.